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(iii) and [serve] primarily as a financing mechanism for states, resulting in increased federal expenditures. Despite the safeguards implemented in the post-2022 approvals of DSHP, CMS has renewed concerns about the same issues originally identified in 2017, the letter states

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Met effectively inhibits the proliferation of RA-FLS by inducing G2/M cell cycle phase arrest, thus upregulating and downregulating phosphorylation of p70S6K and 4E-BP1 [147]

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