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2297-C DEVELOPMENT OF A NOVEL IN VITRO MITOCHONDRIAL TOXICITY TEST BASED ON ATP INHIBITION SUBSTRATE ASSAY Hyunwoo Oh 1 , Hyo Young Lee 1 , Eileen Yoon 2 , Huiyul Park 3 , Sang Bong Ahn 4 , Joo Hyun Sohn 2 and Dae Won Jun 2 , (1)Uijeongbu Eulji Medical Center, (2)Hanyang University College of Medicine, (3)Hanyang University, (4)Eulji Medical Center Background: Mitochondrial toxicity has led to the withdrawal of numerous drugs from the market, highlighting the importance of assessing mitochondrial dysfunction during drug development

Finally, essential trace minerals like zinc and selenium are included to support the formation of metal-binding proteins and reduce the biological availability of toxic elements

The Kyoto Encyclopedia of Genes and Genomes (KEGG) database is a powerful tool for analyzing in vivo metabolic networks

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doi: 10.5696/2156-9614-6-12.50 110 SamuelM

Retatrutide is a triple GLP-1/GIP/Glucagon receptor agonist for laboratory investigation of multi-pathway incretin signalling