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Indeed, high plasma level of TNF- is associated with a marked increase in CRP and IL-6, suggesting an interrelated stimulation of the entire inflammatory cascade (Xia et al., 2016)

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In contrast, the Na 2 CO 3 -extracted PS (S-PS) exhibited more fragmented particles with irregular shapes, likely due to partial structural breakdown induced by the alkaline environment

PMID: 29211849

Increased ROS formation oxidizes neurotransmitters, particularly catecholamines