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In lipid metabolism, many microRNAs regulate cholesterol efflux by targeting ATP-binding cassette transporter (ABCA1/ABCG1)

The effects of prebiotics on gastrointestinal side effects of metformin in youth: a pilot randomized control trial in youth-onset type 2 diabetes

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achieved localized production of IL-12 at the tumor sites through intratumoral delivery of IL-12 mRNA, which induced IFN- expression and promoted TH1 transformation of the tumor microenvironment [31]