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In this condition, pathological changes in the epiphyseal plate were observed with the decreased expression of COLII and GPX1 in the chondrocytes, suggesting a possible association of reduced chondrocyte anabolism and antioxidant capacity with the epiphyseal plate lesions observed in KBD 72

(281) revealed that BMMSC-derived EVs significantly reduced the phosphorylation of JAK1 and STAT1 in DSS-induced UC

Optimizing TCA cycle intermediates supplied in the media can more effectively modulate lactate levels compared to pyruvate or lactate (8)

2a, Supplementary Table 2)

instead, it gains a new ability to facilitate the NADPH-dependent reduction of -KG to D-2-hydroxyglutaric acid (D-2HG), an oncometabolite