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Platinum-based chemotherapy for variant castrate-resistant prostate cancer

Cystathionine produced through transsulfuration is transformed to cysteine of which is oxidized to cysteine sulfinate by the rate limiting enzyme of taurine synthesis cysteine dioxygenase (CDO)

30 There is conflicting data in the literature regarding the use of oral zinc supplementation in the treatment of acne

Another randomized, controlled study investigated the effects of AC isolated from Rehmannia species in patients with immunoglobulin A (IgA) nephropathy

In contrast, DEDTC is a very strong acid ( pK a = 3.37), which would lead to a greater concentration of the active nucleophilic species at physiological pH (faster reaction rate), but would also yield less stable, more reversible adducts (thermodynamically unfavorable)