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pylori infection in WT BMmacs (Supplemental Figure 10 and Supplemental Data Sets 6 and 7)

Abbreviations AD Alzheimers disease ALS Amyotrophic lateral sclerosis APOE Apolipoprotein E ATP adenosine triphosphate HB beta-hydroxybutyric acid FA fatty acids GABA gamma-amino butyric acid KB ketone bodies KD Ketogenic diet MAD Modified Atkins diet MCT medium-chain triglyceride MS multiple sclerosis PD Parkinsons disease PEO progressive external ophtalmoplegia PPAR peroxisome proliferator activated receptor PUFA polyunsaturated fatty acids RCT randomized controlled trial ROS reactive oxygen species SGLT2 sodium-glucose cotransporter-2 UCP uncoupling proteins VLCKD very-low-carbohydrate ketogenic diet

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Studies on turmeric leaves further demonstrate the antioxidant properties attributed to its bioactive compounds

48 In addition, knocking down cth-1 caused a mild decrease in lifespan, 49 and the nuclear receptor nhr-234 and the cytochrome P450 cyp-35A5 were required for remofuscin-induced longevity