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Second, the transformation of TCM interventions faces significant challenges in standardization and regulation

Early biochemical insights (1960s1980s) LPA was first identified in the 1960s as a serum lysophospholipid that induces smooth muscle contraction and promotes platelet aggregation, 15,16,17 establishing the concept that lipids can serve as extracellular signaling molecules

The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas

found that in a small cohort of PASC patients, increases in medium- and long-chain acylcarnitines were among the most pronounced changes in a plasma metabolomic experiment between healthy controls and patients with PASC [48]

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