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2002), although the in vivo toxicities reflect the overall balance both among forms of arsenic and the extent and rate of its elimination

In particular embodiments, the therapeutic agent is selected from an siRNA, a microRNA, an antisense oligonucleotide, and a plasmid capable of expressing an siRNA, a microRNA, or an antisense oligonucleotide, and wherein the siRNA, microRNA, or antisense RNA comprises a polynucleotide that specifically binds to a polynucleotide that encodes the polypeptide, or a complement thereof, such that the expression of the polypeptide is reduced

Neuron 68, 99112

This allows cancer cells to generate energy and intermediate metabolites needed for biosynthesis [99]

The interplay between trace element dysregulation and the pathogenesis of diabetes mellitus highlights the importance of maintaining optimal micronutrient status in the management of this chronic metabolic disorder