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Thus, Quer, as an activator of the GSH system, is a promising natural small molecule for the treatment of cardiac injury

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Preferential transport of glutathione versus glutathione disulfide in rat liver microsomal vesicles, J Biol Chem, 274, 1221312216 Bellomo G, Palladini G, Vairetti M (1997) Intranuclear distribution, function and fate of glutathione and glutathione-S-conjugate in living rat hepatocytes studied by fluorescence microscopy

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Moreover, recent advancements have shown the potential of incorporating these iron and copper-dependent pathways with therapeutic approaches, particularly in the field of nanomedicines and phytocompounds, providing the route to discover novel interventions [11]