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ANDA filers targeting the reformulated product must now clear both the COM patent (if still active) and the formulation patents, or challenge them via Paragraph IV

Mesoporous silica nanoparticles (MSNs), particularly smart mesoporous spheres (SMB-3), exhibit several distinct advantages over existing delivery systems [321]

2 Of note, the range of reported brain GSH concentrations is extremely variable, ranging over an order of magnitude

Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

Articles that were not within the scope of the study, non-English papers, and those without translations were excluded

Affecting approximately 15% of the global population, with a higher prevalence in women, FM significantly impacts patients quality of life, often leading to considerable healthcare costs and loss of productivity