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World J Gastroenterol 21(37):10563 Bauwens E, Joosten M, Taganna J, Rossi M, Debraekeleer A, Tay A, Peter F, Backert S et al (2018) In silico proteomic and phylogenetic analysis of the outer membrane protein repertoire of gastric Helicobacter species Sci Rep 8:15453 Ishijima N, Suzuki M, Ashida H, Ichikawa Y, Kanegae Y, Saito I, Mimuro H (2011) BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity

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For example, genetic KO mice may suffer from developmental compensation, whereas pharmacological reagents may have non-specific effects, both of which may complicate the interpretation of the data