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Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes - Biochem Pharmacol - 1990 Jun 15

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The result is a sustained decline in sex steroid hormones, a state sometimes described medically as chemical castration in men or hypogonadism in both sexes

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(Giuliante et al., 2015) reported pronounced elevation of NNMT protein expression, gene expression, and enzyme activity in the adipose tissue of rats afflicted with MetS