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In A-treated astrocytes, KDS12025 significantly reduced H 2 O 2 levels in control pSicoR-scrambled shRNA (Sc-shRNA) astrocytes, but this effect was abolished in Hb-silenced astrocytes, indicating the necessity of Hb for the action of KDS12025 (Fig

126 The mechanism by which the rapid dispersal of EAAT2 is regulated in response to increased activity has yet to be elucidated

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doi: 10.1007/s40263-016-0370-3 201 ParrachoHMRTBinghamMOGibsonGRMcCartneyAL

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