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HIF-1 is widely expressed and is detected in virtually all innate and adaptive immune populations including macrophages (Cramer et al., 2003), neutrophils (Walmsley et al., 2005), dendritic cells (Jantsch et al., 2008), and lymphocytes (McNamee et al., 2013)

Figure 3 6 AHS and epilepsy AHS is an autosomal recessive genetic disorder caused by biallelic mutations in the POLG gene, which encodes a DNA polymerase responsible for the replication and repair of mtDNA

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Phase 3 data shows up to 71 lb lost in 68 weeks

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