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22, the yields of the polymerase complexes were significantly reduced in the groups expressing L and heterologous VP35 compared to those expressing homologous protein pairs, although the expression levels of L and VP35 were comparable in each group

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This triggers the MAPK cascade, such that Ras-GTP activates Raf [also called MAPK kinase kinase (MAPKKK)], which in turn activates MEK1/2 [MAPK kinase (MAPKK)]

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rather, it also extends its influence to mitigating other cell death pathways, such as apoptosis, necroptosis, pyroptosis, and parthanatos [48]