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The IL-22-responsive transcriptional module is significantly enriched in both mouse colitis models and human UC, with elevated levels of neutrophil-active chemokines such as Cxcl1 , Cxcl2 , Cxcl3 , and Cxcl5 [94]

[9,10,22,27,28,43,53] pCons peptide induce immune tolerance therapy in BWF1 lupus-mice by promoting the generation of autoantigen-specific regulatory T cells that suppressed effector T cells [11,54] and autoantibody-producing B cells

Cai Y, Li YF, Tang LP, Tsoi B, Chen M, Chen H, Chen XM, Tan RR, Kurihara H, He RR (2015) A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice

Finding the human and porcine peptide to have identical sequences, the team concluded 'GLP-1 (PG 78-107 amide) from the small intestine seems to be a new hormone with important functions in the control of metabolism and glucose turnover' (rskov, Bersani, Johnson)

Zhao J, Qi Q, Yang Y, Gu HY, Lu N, Liu W, Wang W, Qiang L, Zhang LB, You QD, Guo QL

For the administration of acetylcysteine, the panel recommended an oral or IV regimen of at least 300 mg/kg delivered during the first 20 to 24 hours of treatment