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Pregnancy and Breastfeeding: Liraglutide is not recommended during pregnancy or breastfeeding due to potential risks and insufficient data on safety

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Glutathione reduces oxidative damage to blood vessels, helping maintain healthy blood pressure levels

While BIO89-100 has been reported to be a balanced agonist of FGF21s receptors in vitro , the smaller magnitude of effect on adiponectin compared to efruxifermin suggest that BIO89-100 may not have maximally stimulated FGFR1c signaling in adipose tissue at the doses tested in humans ( Figure 3B )