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Materials and Methods Animals A total of one hundred adult male Swiss albino mice ( n = 100

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There were no instances of level 2 (less than 54 mg/dL) or level 3 hypoglycemia (severe low blood sugar requiring the assistance of others)

Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition