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However, genetic engineering of proteins may result in impaired functionality and/or increased immunogenicity

J Psychiatry Neurosci 31:326332 Gao K, Ayati M, Koyuturk M et al (2022) Protein biomarkers in monocytes and CD4+ lymphocytes for predicting lithium treatment response of bipolar disorder: a feasibility study with tyramine-based signal- amplified flow cytometry

It is therefore contraindicated in children with clinical suspicion of a hereditary mitochondrial disorder

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Costs were only comparable with procedures currently assigned to MS-DRG 164