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Some research protocols study GHK-Cu in combination with related peptides such as BPC-157, Matrixyl (Palmitoyl Pentapeptide-4)

doi: 10.1007/s00894-012-1505-1 256 ZhangZ

Chaperone-associated selective autophagy Chaperone-assisted selective autophagy (CASA) mediates lysosomal degradation of proteins delivered by a complex comprising HSC70, BAG3, and HSPB8

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The honest answer is that both very low and, in rare cases, very high B12 levels may be linked to shedding, but the strongest evidence points to deficiency as the real concern, not normal supplements