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doi: 10.1038/s41583-023-00729-2 50 JagotFGaston-BretonRChoiAJPascalMBourhyLDorado-DoncelRet al

(6) in the passive skin allergy test of the high-stability reduced glutathione for injection, after the guinea pig is excited, the diameter of blue spots of a tested group and the absorbance of leachate have no difference compared with a negative group, and have obvious difference compared with a positive group, which indicates that the high-stability reduced glutathione for injection (with the batch number of YJ110401) does not generate passive skin allergy reaction on the guinea pig

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Interestingly, sustained activation of ROS can trigger various forms of programmed cell death, including apoptosis, ferroptosis, pyroptosis, necroptosis, oxeiptosis, NETosis, parthanatos, autophagy, necrosis and immunogenic cell death [22, 213, 214] (Fig

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