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10.1111/j.1365-2036.2006.02943.x 84 SchatzR

As an important component in the electron transport chain during cellular respiration, coenzyme Q10 (CoQ10) (ubiquinone) mediates electron transfer and results in the shifting of hydrogen ions into the mitochondrial intermembrane space to form a hydrogen ion concentration gradient, ultimately required for the formation of ATP [11]

Indeed, the recent, much-hyped report of increased cancer in aspartame-dosed rodents (3) actually made me less nervous about aspartame: it (a) really didn't clearly show any increased cancer risk (they hyped up non-statistically-significant elevations in incidence of some cancers late in life, but also NS decreases in others), and indeed (b) reported identical survival curves between aspartame-treated and untreated animals (if anything, it looked like females given the highest dose lived LONGER on average than untreated animals)

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Cell 61:9317 Simani L, Rezaei O, Ryan F, Sadeghi M, Hooshmandi E, Ramezani M et al (2020) Research paper: coenzyme Q10 insufficiency contributes to the duration and frequency of seizures in epileptic patients

6 January 2004