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Abstract Oxalate homeostasis is maintained through a delicate balance between endogenous sources, exogenous supply and excretion from the body

Benjamin Boury-Jamot, Centre Hospitalier Universitaire Vaudois (CHUV), Switzerland Updates Copyright 2018 Delhey, Tippett, Rose, Bennuri, Slattery, Melnyk, James and Frye

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Usually such buffer should have pH of around 7.0 - 8.0 to facilitate efficient interaction between GST and its substrate glutathione, protease inhibitors (such as PMSF) to prevent protein degradation

Patients commonly experience neurocognitive deficits such as reduced working memory, slower processing speed and impaired executive function, together with affective symptoms including depression, apathy and anxiety, which heighten the overall neuropsychiatric burden (69, 70)

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