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Chronic fatigue possesses an impact on the social, emotional, and occupational functioning of an individual, and may cause disability (Finsterer and Mahjoub 2014)

Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b

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They noted that CFA 13 consists of 20 separate genes, and CFA 14 have 11 such genes, and that "some of these genes are good candidate genes for the development of MMVD"