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Henan Tradit Chin Med 2021;41:3925

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Primary bile acids (e.g., cholic acid) are converted into secondary bile acids (e.g., deoxycholic acid) via microbial 7-dehydroxylation, which activate FXR and TGR5 receptors to not only improve glucose and lipid metabolism in diabetic patients but also exert potent anti-inflammatory effects (Willart et al., 2012)

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