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HE staining analysis results exhibited that the COPD rats treated with NAC and oe-VWF had less inflammatory cell infiltration, less destruction of the alveolar septum, and complete columnar epithelial cells compared with those treated with NAC and oe-NC, while opposite trends were noted in the presence of NAC + oe-VWF compared with oe-VWF alone (Fig

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Accordingly, major advances have occurred in understanding the role of these oxidants in physiology and disease, including the nervous, cardiovascular and immune systems, skeletal muscle and metabolic regulation as well as ageing and cancer

[13]Current Patent Assignee: BEIJING PUQI PHARMACEUTICAL TECH - WO2024/153226, 2024, A1 Location in patent: Page/Page column 19-20