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Decades of effort to inhibit MYC and TP53 are beginning to translate into tangible progress, with several compounds entering clinical trials and showing early signs of safety and efficacy (90)Whitfield JR, et al

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10.1021/bi00201a009 7 AyalaA.MuozM

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Western blotting The HepG2 cells (2 10 6 cells per dish) were seeded in 10 cm culture dishes and incubated for 24 h, followed by treatment with various concentrations of TB m A-Glu (0, 0.5, 1.0, 2.0, 2.5, and 5.0 M) for 12 h