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Younossi Alimentary Pharmacology & Therapeutics .2025

This means less glutathione & more free radicals which end up damaging blood cells

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[7] Causes of upper gastrointestinal bleeding that may result in melena include malignant tumors affecting the esophagus, stomach or small intestine, hemorrhagic blood diseases, such as thrombocytopenia and hemophilia, gastritis, stomach cancer, esophageal varices, Meckel's diverticulum and Mallory-Weiss syndrome