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Serum superoxide dismutase (SOD) and glutathione (GSH) activities were also significantly increased in all NPs-treated groups compared with the control, indicating an upregulation of enzymatic and non-enzymatic antioxidant mechanisms

Hepatic toxicity with long-term use Nitrofurantoin-induced liver injury is rare with short courses but becomes a more meaningful concern with long-term use

Natural Compounds and Autophagy: Allies Against Neurodegeneration

Although detrimental for cell replication, moderate iron deficiency does not necessarily induce cell death and could render cells quiescent and resistant, which can lead to tumor regrowth upon treatment removal

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Further, NASO B12 was well-tolerated throughout the treatment period.[] Patients on metformin therapy receiving NASO B12 should also be instructed that they will require weekly intranasal administration of NASO B12 spray in each nostril after correction of vitamin B12 deficiency for the remainder of their lives