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Male, 18-week-old C57BL/6J mice, maintained on a 60% high-fat diet (HFD

Yet, researchers should note that the peptide has not been researched regarding its safety following subcutaneous administration

For purification, a 5 ml StrepTrap HP (GE Healthcare) was equilibrated with at least five column volumes of lysis buffer

Following an apoptotic stimulus, Bax is activated and translocates to the mitochondria, where it undergoes a conformational change and inserts into the OMM

The absence of safety data in these populations means that use should be avoided or approached with extreme caution and specialized medical supervision