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Hydrophobic extracts were reconstituted in 100 L 5:4:1 EtOH/MeOH/water

3.3.1 Parkinsons disease (PD) The primary pathologic hallmarks of PD are loss of dopaminergic neurons located in an area of the brain called the substantia nigra pars compacta, and the presence of Lewy bodies, intracellular aggregates of misfolded -synuclein, in dopaminergic neurons and likely contribute to the death of these neurons

Lyophilized research products should be stored in a cool, dry environment prior to preparation to help maintain long-term stability and purity

doi: 10.1016/j.jacc.2021.11.029 3

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In vitro , MUFA has shown the ability to induce the expression of the adiponectin gene via PPAR activation, which would result in decreased production of pro-inflammatory molecules such as IL-6 and tumour necrosis factor (TNF)-alpha (139) Polyunsaturated fatty acids, such as omega-3 fatty acids (n-3 PUFA), are mostly found in eggs, nuts, and fish, whereas omega-6 fatty acid (n-6 PUFA) is predominantly present in sunflower and other vegetable oils