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A mature rat weighing more than 250 g (1416 weeks old) is the most suitable because younger rats can present technical problems, whereas older rats are more prone to respiratory infections and fat accumulation

Mino M, Sano A, Kakazu E, Matsubara H, Kakisaka K, Kogure T

One-carbon metabolism supports DNA synthesis, repair, and methylation, which is essential for neuronal development [35]

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Lv, Recent advances in urea electrocatalysis: Applications, materials and mechanisms