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20 These three CRPC subtypes manifest distinct responses to Enza: AR +/hi LNCaP-CRPC exhibits an acute and transient sensitivity and AR cyto LAPC4-CRPC and VCaP-CRPC a more drawn-out sensitivity whereas AR -/lo LAPC9-CRPC shows no response to Enza

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After 40 weeks, 78% to 85% of adults taking Mounjaro achieved an HbA1c below 7%, compared with 23% of adults taking a placebo