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The implications for studies in Metabolic & Weight Research are significant, and it all starts with this elegant, targeted mechanism

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Evidence stratification and clinical translation challenges To address the critical issue of insufficient differentiation between evidence levels, we systematically organize the core findings related to the NTFs-mitochondria axis by research model, clarify their evidence strength, and highlight translational gaps in the following Table 1

This provides a wide range of health benefits

The inner NP is a gel-like tissue that is rich in randomly arranged collagen, such as aggrecan (Acan), and radially arranged elastin fibers, which provide a stable structural basis for bearing the spinal stress load and protecting nucleus pulposus cells (NPCs) [4,5,6]