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BPTES treatment of MRL/lpr mice reduced glycolysis and significantly decreased double-negative T cells (CD3 + CD4 - CD8 - cells), the urinary albumin/creatinine ratio, glomerular nephropathy score, and T-cell infiltration with IL-17A in the kidneys, relieving the EAE disease activity (9)

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Linear ion trap (2D ion trap) The space charge effect represents a major limitation for the three-dimensional (3D) ion trap, mainly due to its small confinement volume

Weeks 2 to 4: Significant functional improvements reported