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1972;49:383-90 pubmed Woodbury R, Hardy S, Randall L

While COP1 can function independently, it can also be incorporated into CULLIN4-RING ubiquitin ligase (CRL4) complexes through the DET1 adaptor protein

Sureshbabu A, Ryter SW, Choi ME (2015) Oxidative stress and autophagy: crucial modulators of kidney injury

Nanomedicine (Lond) 11 (18), 24432456

However, glutathione levels can drop gradually if one maintains poor lifestyle choices or specific medical conditions

Notably, cellular iron availability influences TRP and KYN metabolism through haem biosynthesis, because haem is an essential cofactor for IDO1 and TDO2 49