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Based on our literature review we identified 147 relevant reproductive toxicity studies in rats that have reported on the effects of various chemicals on NR in male offspring, as well as co-reporting of AGD (Supplementary Table S1)

Conversely, isoniazid and pyrazinamide (tuberculosis drugs) are structural analogs of niacin that can interfere with niacin metabolism, potentially precipitating pellagra in rare cases

Consequently, they are sold strictly for in-vitro research and laboratory purposes only

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