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"I thought people would just stop going to pubs, that they wouldn't get the business and were going to close - and a few did," she says

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The alternative is the death of a sector that was growing, he added.

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For example, treatment with nicotine and e-cig fluid led to significant induction of mRNA expression for CYP2A6, CYP2E1 , CYP1A1 and CYP2S1 following in an in vitro model of human brain blood barrier, the hCMEC/D3 cell line 45