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Experimental data showed that intravenously injected HABN accumulated in tumor cells and tumor-associated myeloid cells, (possibly as a result of the enhanced permeability and retention effect and targeting of CD44, ROS effect) allowing SC144 to act: radicalizing macrophages into the M1 phenotype, inducing killing effect of CD8 + T cells, enhanced PD-L1 expression in tumor cells and inducing immunogenic cell death in vitro

Cambridge, United Kingdom: The Francis Crick Papers

Carvalho-e-Silva AP

10.2152/jmi.55.167 68 SekiM.NarusakaM.IshidaJ.NanjoT.FujitaM.OonoY.et al (2002)

The most important variations that occur in the real ocean arise from changes in the carbon system, and in the concentrations of Calcium (Ca 2+ ) and the macronutrients nitrate (NO 3 - ) and silicic acid (Si(OH) 4 ) (Table 2)

Plant Mol Biol 80:571585 Zhang H, Yang Y, Wang C, Liu M, Li H, Fu Y, Wang Y, Nie Y, Liu X, Ji W (2014) Large-scale transcriptome comparison reveals distinct gene activations in wheat responding to stripe rust and powdery mildew