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Retrieved January 15, 2017

What the clinical trial evidence shows Mounjaro (tirzepatide) ~22.5% average body weight lost at 72 weeks ( SURMOUNT-1, 15mg) Wegovy (semaglutide) ~14.9% average body weight lost at 68 weeks ( STEP-1 , 2.4mg) Saxenda / Nevolat (liraglutide) ~5-8% average body weight lost at 56 weeks ( SCALE trial ) For context, prior to GLP-1 medications, the most effective non-surgical weight loss intervention available was a combination of intensive lifestyle modification and Orlistat , which typically produces 5 to 8% weight loss

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The Whipple procedure, also known as pancreaticoduodenectomy, is a complex surgical treatment primarily used to remove cancerous tumors within the head of the pancreas

The trial was 12 weeks

643 Long-acting PEGylated C-peptide C-peptide has neuroprotective properties in T1DM, improving nerve blood flow and NCV and increasing expression of beneficial neurotrophic factors