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Description

Cell Metabolism, 22(1), 31-53

J.WongM.-L.LicinioJ.et al

Our previous work showed that expression of glycoprotein 130 (gp130) receptor on intestinal epithelial cells mediates GAP formation via induction of the muscarinic acetylcholine receptor 4 (mAChR4) receptor on goblet cells promoting protection from ethanol-induced liver disease

In line with this, Fento-1 was more potent against HT-1080 cells that were treated with low doses of doxorubicin for a prolonged period of time (Extended Data Fig

Depending on the formula, infusions take between 3060 minutes

Interestingly, free curcumin was more effective as an anticancer agent than its metal complexes, matching the activity of the reference drug doxorubicin