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Inhibiting System Xc- and inactivating GSH peroxidase-4 (GPX4) causes cellular glutathione (GSH) depletion and impaired ROS scavenging, resulting in disruption of cellular redox homeostasis, accumulation of ROS in the lipid peroxidation or Fenton reaction, and ultimately cell death (Shi et al., 2021)

The 5 portion of the HOXA gene cluster is the source of the 3,764-nucleotide-long non-coding RNA (lncRNA) known as HOXA transcript at the distal tip (HOTTIP)

[DOI] [PubMed] [Google Scholar] 325.Franco DC, de Carvalho GS, Rocha PR, et al

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[159] If more recent data on DSH eligibility become available before the final rule, we would use such data in the final rule