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Description

and (iv) Demonstrating that interventions based on such immune phenotyping can improve prognosis

Thus, dysfunctional carbonylated proteins accumulate as covalently crossed protein aggregates, making them highly resistant to proteolysis, thereby affecting the functional integrity of cells during the aging and disease processes

Circulation 133 , 826839 (2016)

Using microtubule staining, we observed that KU-57788 treatment caused hallmark features of mitotic catastrophe in ATC cells, including chromosomal misalignment and multipolar spindle formation during cell division (Fig