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These discoveries have given rise to the idea that bipolar disorder is a bioenergetic and metabolic disease with psychiatric manifestations, and that disruptions in the molecular and cellular signalling networks that regulate brain energy metabolism in a biphasic manner are a primary, sufficient cause of bipolar disorder-related phenomena [189]

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Hormone replacement therapy (HRT) Though it may be considered a more intense route than a supplement, HRT is a relatively safe and effective option for people dealing with certain hormone-related concerns

Week 8+: Continued improvement with consistent daily use

10.1021/acs.chemrestox.6b00357 Chem

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