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Gamma knife treatment for multiple metastatic brain tumors compared with whole-brain radiation therapy

RNA was collected from these samples, and quantitative real-time PCR was performed to measure gene expression levels

KEAP1 is a repressor of NRF2 activity and plays a key role in its regulation [21, 22]

Lidocaine (rare)

Consult with a dermatologist if you have concerns about product compatibility

This finding, together with the previous studies indicating the capacity of SIRT2 to modulate the gene expression of SOD2 by affecting the activity of FOXO3a (Wang et al., SIRT2 is a NAD + -dependent enzyme (Schemies et al., + levels can produce decreased SIRT2 activity (Skoge et al., + treatment-induced increases in the intracellular NAD + levels could lead to increased SIRT2 activity, resulting in the increases in the Nrf2 activity, GCL levels and GSH/GSSG ratios