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M.Al MalikY.MakkawiS.ZeddeA.CerchiaroG

The samples are anonymous and no personal or medical information were used in this study

The Bcl-2 family proteins regulate apoptosis by altering mitochondrial membrane permeabilization which leads to the release of apoptogenic factors such as cytochrome c , procaspases, and apoptosis inducing factor (AIF)

Glutamine homeostasis and mitochondrial dynamics

LAT2 plays a critical role for the uptake of neutral amino acids, including glutamine, which are essential nutrients for the growth and proliferation of cancer cells, and are crucial to the biosynthesis of products such as nucleic acids and non-essential amino acids 15

10.1111/j.1753-4887.2007.tb00285.x Nutr