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[697] Section 1860D-14B(b)(5)(B)(ii) of the Act further states that for a Part D rebatable drug, the term line extension means, a new formulation of the drug, such as extended release formulation, but does not include an abuse-deterrent formulation of the drug (as determined by the Secretary), regardless of whether such abuse-deterrent formulation is an extended release formulation. This language is identical to the definition of line extension in section 1927(c)(2)(C) of the Act

10.1038/cdd.2012.159 98 LeeJ.YunN.KimC.SongM

also showed that MIYAIRI 588 had new potential to relieve NAFLD

Is AOD-9604 safe for long-term use

Instead of being flushed away, it starts to attack liver cells, leading to oxidative damage and cellular stress

Autophagy is primarily regulated by signaling pathways such as the serine/threonine protein kinase mammalian target of rapamycin (mTOR), AMP activated protein kinase (AMPK), and sirtuins