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With regard to muscle atrophy in cachexia, studies have focused on different cell signaling pathways, including the myostatin pathway, TNF- pathway, TGF/p38/MAPK pathway, NFB pathway, IL-6 pathway [12], Notch/-catenin pathway, corticosteroid pathway, IGF/Akt pathway [54], and FOXO1 /FOXO3a pathway [55], among others

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The compound has not progressed through standard pharmaceutical-development trials for any therapeutic indication

amylovora generates oxidative stress even in compatible plant-pathogen interactions could be linked to its functional hrp gene cluster

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