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Selenium 55 g

10.1016/j.ebiom.2019.03.057 37 LiuB.WangW.ZhuX.SunX.XiaoJ.LiD.et al (2018)

(2022) conducted an association study on brain DNA methylation and cognitive trajectory changes in 636 patients and found abnormal DNA methylation modifications in claudin 5 (CLDN5), an important protein for the BBB

The participants were divided into two cohorts that alternated the timing of vitamin C supplementation: cohort 1 received vitamin C during the initial six-week phase, whereas cohort 2 received it during the subsequent six-week phase